The uncertainty of the world's economy and geopolitics leaves Asian institutional investors with many uncertainties, as they ponder how best to strategically and tactically prepare their portfolios. 

Northern Trust has identified six megatrends or themes that it believes will be among the most dominant over the coming five years, and which investors should take stock of as they consider their investment plans.

From concerns over high valuations to a persistent lack of inflation and a longstanding level of tension between the US and China, the world is set to become a more complicated place to navigate over the coming years.